30 responses to “FYI: Aspergillus brasiliensis Replaces Aspergillus niger”

  1. larissa


    Is it possible to distingish A. niger ATCC 6275 from A. braziliensis ATCC 16404 morphologically?

    I noticed that in Petri dish, if observe the lower plate, below the fungi colony, they look different, but I don´t if can be considered.

    I will be waiting for you reply.


  2. Pavan Kumar

    Dear Sir!

    As per ATCC , A. brasliensis ATCC 16404 name replaced instead of A.niger.
    But U.S pharmacopoeia (USP32) still in some Pages mentioned as A.niger.(page no 69),But in some pages mentioned as A.brasilinsis. Why there in no consistency?
    may i know the reason please?
    thanks and regards
    Pavan Kumar
    Qc Microbiology

  3. Suresh

    I would like to know the confirmation of Aspergillus brasiliensis

  4. Nhu Thuy

    Could you please tell me the conditions and techniques in details to culture and subculture the A. Brasiliensis????
    Thanks so much.

  5. Nhu Thuy

    Dear Sir,
    Thanks for your answer. But, I read some references say that we use Potato Dextrose agar to grow A. Brasiliensis, so which medium is better, Sir??
    Thanks again for your support!

  6. Dave Rottjakob, ATS Labs

    Hi Nhu,
    Thank you for your question. We have used Potato Dextrose agar but find that Sabouraud agar is a better medium for Aspergillus brasiliensis.

    Dave Rottjakob
    Director of Microbiology and New Business Development
    ATS Labs.

  7. Nhu Thuy

    I appriciate your information so much. This helps me a lot in my job. I hope that this web becomes one of my favourite references. Thanks again.
    P.s: By the way, can you tell me the medium and conditions for growing C. Sporogenes.
    I’ve read many information but i also confuse about this.
    Thank you so much.
    Nhu Thuy

  8. balanagaraj

    so which ATCC no i have to use in my biopharma industry for A.niger?

  9. balanagaraj

    thanks 4 your reply we are using a.niger 16404. currently for rabies vaccine through cellcluture

  10. Leman

    Dear Sİrs,

    Dear Sirs,

    We are a global company working on Plastic and construction Turkey .We have one of the largest PVC profile production plants in the Middle East and Europe which extends on an area of 550.000 m2 at Antalya Industrial and Commercial Zone.
    Nowadays we are looking for some microorgansms to make some tests on our wood composite product , we wonder about the formation of mildew during the years , so we will make a test in enviromental cabin chamber , for this test we recommended to but aspergillus brasilliensis ATCC™ 16404 (DSM 1988) do you think is that the same effect for us if we buy aspergillus niger ATCC 6275 ? ı mean are they same? Waiting for your reply..

    Thanks and regards.

  11. Nhu Thuy

    Dear Sir,
    I would like to exent my thanks to all you. I learn a lot of knowledge from this web.
    I hope that it will become more popular. By the way, can you help me to know where is the Pseudomonas luteola usually isolated???
    Because I found a lot of information but I still cannot know its origination.
    Thank you a lot for your help.
    Best regards.

  12. J.Renugopal

    Hi Sir,

    we are doing mold identification up to genus level by morphology and staining, as u said we can’t differentiate by morphologically in this case how we can give the result , is there any difference in microscopic observation

    Setsco services pte ltd

  13. J.Renugopal

    Thanks for your reply

  14. Larry Callahan

    I was just curious how the decision was made to change this name and why the name of Aspergillus brazilensis was not merged into Aspergillus niger. There are a number of products on the market that refer to Aspergillus niger ( allergenic extracts, enzymes, etc) and pathology related to Aspergillus niger if we were to change the name of these products or the result of tests it would cause a great deal of confusion and potential safety issues. Is there a public process where these name changes get vetted before they become official.

  15. Rams

    Good Morning Mr David Rottjakob,

    Could you please clarify, Is it required to perform Antimicrobial Effectiveness test to an second generation Cephalosporin antibiotic which is of multidose.

    Generally we perform the Antimicrobial Effectiveness test to preservatives, since the product itself is an antibiotic,no preservatives are added to the above said antibiotic Injection.

    We are requested by agency to provide USP or equivalent testing for the reconstituted drug product.

    Please suggest.


  16. Shaikh Meraj

    Is there any specific reason for changing the name of niger to brasilliensis
    Thanks in advance

  17. Theresa D

    Can you advise the optical density for Aspergillus brasiliensis? I’m trying to validate the USP 61. Thank you.

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